{"id":100,"date":"2025-05-28T11:27:09","date_gmt":"2025-05-28T11:27:09","guid":{"rendered":"https:\/\/dralokkalyani.com\/blog\/?p=100"},"modified":"2025-05-28T11:27:10","modified_gmt":"2025-05-28T11:27:10","slug":"what-is-rheumatoid-factor","status":"publish","type":"post","link":"https:\/\/dralokkalyani.com\/blog\/what-is-rheumatoid-factor\/","title":{"rendered":"What is Rheumatoid Factor"},"content":{"rendered":"\n<p><strong>Rheumatoid Factor (RF)<\/strong> is an <strong>autoantibody<\/strong>\u2014a type of protein produced by immune system\u2014that can <strong>attack your body\u2019s own tissues<\/strong> instead of foreign antigens like bacteria and viruses.<\/p>\n\n\n\n<p>Even if your <strong>rheumatoid factor (RF) is negative<\/strong>,You can have Rheumatoid Arthritis . This condition is known as <strong>seronegative rheumatoid arthritis<\/strong>.<\/p>\n\n\n\n<p><\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>Seronegative vs. Seropositive RA<\/strong><\/h3>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>Seropositive RA<\/strong>: RF and\/or anti-CCP (anti-cyclic citrullinated peptide) antibodies are <strong>positive<\/strong>.<\/li>\n\n\n\n<li><strong>Seronegative RA<\/strong>: RF and <strong>anti-CCP antibodies are negative<\/strong>, but clinical symptoms and imaging still support a diagnosis of Rheumatoid Arthritis<\/li>\n<\/ul>\n\n\n\n<h3 class=\"wp-block-heading\"> <strong>Anti-CCP is More Specific<\/strong><\/h3>\n\n\n\n<p>If RF is negative, a positive <strong>anti-CCP<\/strong> test may still confirm RA. If both are negative, the diagnosis may still be made based on symptoms and imaging.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Rheumatoid Factor (RF) is an autoantibody\u2014a type of protein produced by immune system\u2014that can attack your body\u2019s own tissues instead of foreign antigens like bacteria and viruses. Even if your rheumatoid factor (RF) is negative,You can have Rheumatoid Arthritis . This condition is known as seronegative rheumatoid arthritis. Seronegative vs. Seropositive RA Anti-CCP is More [&hellip;]<\/p>\n","protected":false},"author":4,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[1],"tags":[],"class_list":["post-100","post","type-post","status-publish","format-standard","hentry","category-blog"],"_links":{"self":[{"href":"https:\/\/dralokkalyani.com\/blog\/wp-json\/wp\/v2\/posts\/100","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/dralokkalyani.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/dralokkalyani.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/dralokkalyani.com\/blog\/wp-json\/wp\/v2\/users\/4"}],"replies":[{"embeddable":true,"href":"https:\/\/dralokkalyani.com\/blog\/wp-json\/wp\/v2\/comments?post=100"}],"version-history":[{"count":1,"href":"https:\/\/dralokkalyani.com\/blog\/wp-json\/wp\/v2\/posts\/100\/revisions"}],"predecessor-version":[{"id":101,"href":"https:\/\/dralokkalyani.com\/blog\/wp-json\/wp\/v2\/posts\/100\/revisions\/101"}],"wp:attachment":[{"href":"https:\/\/dralokkalyani.com\/blog\/wp-json\/wp\/v2\/media?parent=100"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/dralokkalyani.com\/blog\/wp-json\/wp\/v2\/categories?post=100"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/dralokkalyani.com\/blog\/wp-json\/wp\/v2\/tags?post=100"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}